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Today we featured Nobel Laureate Dr. Gregg L. Semenza in our Leaders in Medicine Series. Dr. Semenza is a professor of genetic medicine, pediatrics, radiation oncology, molecular radiation sciences, biological chemistry, medicine, and oncology at Johns Hopkins who was awarded the Nobel Prize in 2019 for his team’s work on mechanisms of oxygen regulation. He has long been a leader in this field, specifically helping to elucidate genetic and cellular adaptations to hypoxia, including the discovery of hypoxia-inducible factor 1 (HIF-1). The discovery of this protein and its microbiologic role promises further understanding (and potential therapeutic targets) of widely pervasive diseases such as cardiovascular disease, anemia, diabetes, and cancer.

Department of Medicine Grand Rounds
January 18, 2022

Hypoxia-Inducible Factors in Physiology and Medicine

Nobel Laureate
Gregg L. Semenza, MD, PhD
Professor of Genetic Medicine
Professor of Biological Chemistry, Medicine, Oncology, Pediatrics, and Radiation Oncology and Molecular Radiation Sciences
Johns Hopkins School of Medicine

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